Ireland vs Wales: Nick Timoney to start and Tommy O'Brien misses outElsewhere, Jamison Gibson-Park will win his 50th Test cap in green, while uncapped Ulster scrum-half Nathan Doak is in line for his Ireland debut off the bench.
England make nine changes to team for Six Nations game against Italy in RomeThere are a further three positional switches in Steve Borthwick’s starting XV.
Paul O’Connell plays down Triple Crown talk ahead of Ireland’s clash with WalesAndy Farrell’s side return to Guinness Six Nations action at home to winless Wales on Friday evening after celebrating a record 42-21 victory at Twickenham in round three.